human PLCD3 Over-expression AAV

Name 
AAV-h-PLCD3
Cat No 
AAV-219122
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PLCD3.

AAV-219122
AAV-h-PLCD3

Ready-to-use AAV expressing Human PLCD3 (phospholipase C delta 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
PLC-delta-3
Description (Vector)
PLCD3 encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4,5-bisphosphate to generate the second messengers diacylglycerol and inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids.
Gene ID
113026
Gene Name (Vector)
phospholipase C delta 3
Gene Symbol
PLCD3
HGNC ID
HGNC:9061
ORF Size (aa)
2370
ORF Size (bp)
2370 bp
RefSeq ID
NM_133373
RefSeq Synonyms
NM_133373, BC072384,
Species
human
UniGene ID
Hs.380094

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.