human PHPT1 Over-expression AAV

Name 
AAV-h-PHPT1
Cat No 
AAV-218857
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PHPT1.

AAV-218857
AAV-h-PHPT1

Ready-to-use AAV expressing Human PHPT1 (phosphohistidine phosphatase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
14 kDa phosphohistidine phosphatase; CGI-202; epididymis secretory sperm binding protein Li 132P; HEL-S-132P; HSPC141; Phosphohistidine phosphatase 1; PHP; PHP14; PHPT1; protein histidine phosphatase; protein janus-A homolog; sex-regulated protein janus-a
Description (eCommerce)
PHPT1 is enzyme that catalyzes the reversible dephosphorylation of histidine residues in proteins. It may be involved in the dephosphorylation of G-beta and ATP citrate lyase and in negatively regulating CD4 T lymphocytes by dephosphorylation and inhibition of KCa3.1 channels. [taken from NCBI Entrez Gene (Gene ID: 29085)].
Description (Vector)
PHPT1 is an EDTA-insensitive phosphohistidine phosphatase that catalyzes the dephosphorylation of phosphopeptide I (Ek et al., 2002 (PubMed 12383260)).(supplied by OMIM, Mar 2008)
Gene ID
29085
Gene Name (eCommerce)
phosphohistidine phosphatase 1
Gene Name (Vector)
phosphohistidine phosphatase 1
Gene Symbol
PHPT1
HGNC ID
HGNC:30033
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
378
Protein Name (eCommerce)
14 kDa phosphohistidine phosphatase
RefSeq ID
NM_014172
RefSeq Synonyms
NM_014172, NM_001287343, NM_001287342, NM_001135861, BC024648,
Research Areas
Cytoskeleton,EGFR Signaling,Immunology,Kinase/Phosphatase,Metabolism/Metabolic Process,Phosphatase,Signal Transduction,T-cell Receptor Signaling
Research Areas (Faceted)
cell_biology,immunology,metabolism,signal_transduction
Species
human
Target Sentence
PHPT1 is enzyme that catalyzes the reversible dephosphorylation of histidine residues in proteins. It may be involved in the dephosphorylation of G-beta and ATP citrate lyase and in negatively regulating CD4 T lymphocytes by dephosphorylation and inhibition of KCa3.1 channels. [taken from NCBI Entrez Gene (Gene ID: 29085)].
UniGene ID
Hs.409834
UniProt ID (eCommerce)
Q9NRX4

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.