human PGM3 Over-expression AAV

Name 
AAV-h-PGM3
Cat No 
AAV-218764
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PGM3.

AAV-218764
AAV-h-PGM3

Ready-to-use AAV expressing Human PGM3 (phosphoglucomutase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
acetylglucosamine phosphomutase; AGM1; IMD23; N-acetylglucosamine-phosphate mutase; N-acetylglucosamine-phosphate mutase 1; PAGM; PGM 3; phosphoacetylglucosamine mutase; Phosphoglucomutase-3
Description (eCommerce)
Phosphoglucomutase-3 (PGM3) is a member of the phosphohexose mutase family. PGM3 mediates both glycogen formation and utilization by catalyzing the interconversion of glucose-1-phosphate and glucose-6-phosphat [taken from NCBI Entrez Gene (Gene ID: 5238)].
Description (Vector)
PGM3 encodes a member of the phosphohexose mutase family. The encoded protein mediates both glycogen formation and utilization by catalyzing the interconversion of glucose-1-phosphate and glucose-6-phosphate. A non-synonymous single nucleotide polymorphism in this gene may play a role in resistance to diabetic nephropathy and neuropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
5238
Gene Name (eCommerce)
phosphoglucomutase 3
Gene Name (Vector)
phosphoglucomutase 3
Gene Symbol
PGM3
HGNC ID
HGNC:8907
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1629
ORF Size (bp)
1629 bp
Protein Name (eCommerce)
Phosphoacetylglucosamine mutase
RefSeq ID
NM_015599
RefSeq Synonyms
NM_015599, NM_001199919, NM_001199918, NM_001199917, BC001258,
Research Areas
Metabolism/Metabolic Process,Translational Control
Research Areas (Faceted)
cell_biology,metabolism,transcription_translation
Species
human
Target Sentence
Phosphoglucomutase-3 (PGM3) is a member of the phosphohexose mutase family. PGM3 mediates both glycogen formation and utilization by catalyzing the interconversion of glucose-1-phosphate and glucose-6-phosphat [taken from NCBI Entrez Gene (Gene ID: 5238)].
UniGene ID
Hs.708038
UniProt ID (eCommerce)
O95394

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.