human PGGT1B Over-expression AAV

Name 
AAV-h-PGGT1B
Cat No 
AAV-218734
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PGGT1B.

AAV-218734
AAV-h-PGGT1B

Ready-to-use AAV expressing Human PGGT1B (protein geranylgeranyltransferase type I subunit beta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BGGI; GGTI
Description (Vector)
Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1994 (PubMed 8106351)). The enzyme is composed of a 48-kD alpha subunit (FNTA; MIM 134635) and a 43-kD beta subunit, encoded by the PGGT1B gene. The FNTA gene encodes the alpha subunit for both GGTase-I and the related enzyme farnesyltransferase.(supplied by OMIM, Mar 2010)
Gene ID
5229
Gene Name (Vector)
protein geranylgeranyltransferase type I subunit beta
Gene Symbol
PGGT1B
HGNC ID
HGNC:8895
ORF Size (aa)
1131
ORF Size (bp)
1131 bp
RefSeq ID
NM_005023
RefSeq Synonyms
NM_005023, BC118496, BC111924,
Species
human
UniGene ID
Hs.254006

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.