human PGGT1B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PGGT1B.
shAAV-218734
AAV-h-PGGT1B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PGGT1B (protein geranylgeranyltransferase type I subunit beta). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BGGI; GGTI
Description (Vector)
Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1994 (PubMed 8106351)). The enzyme is composed of a 48-kD alpha subunit (FNTA; MIM 134635) and a 43-kD beta subunit, encoded by the PGGT1B gene. The FNTA gene encodes the alpha subunit for both GGTase-I and the related enzyme farnesyltransferase.(supplied by OMIM, Mar 2010)
Gene ID
5229
Gene Name (Vector)
protein geranylgeranyltransferase type I subunit beta
Gene Symbol
PGGT1B
HGNC ID
HGNC:8895
ORF Size (aa)
1131
ORF Size (bp)
1131 bp
RefSeq ID
NM_005023
RefSeq Synonyms
NM_005023, BC118496, BC111924,
Species
human
UniGene ID
Hs.254006
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.