human PFKFB2 Over-expression AAV

Cat. No: AAV-218669

Availability: 3-5 weeks

Name: AAV-h-PFKFB2

This is an AAV expressing Human PFKFB2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PFKFB2
Gene Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
Gene ID: 5208
Gene Synonyms: PFK-2/FBPase-2
ORF Size: 1518 bp
RefSeq#: BC069385
Gene Description: PFKFB2 is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene.
UniGene ID: Hs.282702
HGNC ID: HGNC:8873