human PDE1C Over-expression AAV

Name 
AAV-h-PDE1C
Cat No 
AAV-218463
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PDE1C.

AAV-218463
AAV-h-PDE1C

Ready-to-use AAV expressing Human PDE1C (phosphodiesterase 1C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
cam-PDE 1C; hCam-3; Hcam3
Description (Vector)
Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1C, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 (PubMed 1326532)).(supplied by OMIM, Oct 2009)
Gene ID
5137
Gene Name (Vector)
phosphodiesterase 1C
Gene Symbol
PDE1C
HGNC ID
HGNC:8776
ORF Size (aa)
1905
ORF Size (bp)
1905 bp
RefSeq ID
NM_005020
RefSeq Synonyms
NM_005020, NM_001322059, NM_001322058, NM_001322057, NM_001322056, NM_001322055, NM_001191059, NM_001191058, NM_001191057, NM_001191056, BC022525, BC022479,
Species
human
UniGene ID
Hs.655694

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.