human NT5C3 Over-expression AAV

Name
AAV-h-NT5C3

Cat No
AAV-217137

Availability
4-5 weeks

This is an AAV expressing Human NT5C3A.

AAV-217137

AAV-h-NT5C3

Ready-to-use AAV expressing Human NT5C3A (5′-nucleotidase, cytosolic IIIA). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

cN-III; hUMP1; NT5C3; p36; P5'N-1; P5N-1; PN-I; POMP; PSN1; UMPH; UMPH1

Description (Vector)

NT5C3 encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded protein is the type 1 isozyme of pyrimidine 5' nucleotidase and catalyzes the dephosphorylation of pyrimidine 5' monophosphates. Mutations in this gene are a cause of hemolytic anemia due to uridine 5-prime monophosphate hydrolase deficiency. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and pseudogenes of this gene are located on the long arm of chromosomes 3 and 4.

Gene ID

51251

Gene Name (Vector)

5'-nucleotidase, cytosolic IIIA

Gene Symbol

NT5C3A

HGNC ID

HGNC:17820

ORF Size (aa)

894

ORF Size (bp)

894 bp

RefSeq ID

NM_016489

RefSeq Synonyms

NM_016489, NM_001166118, NM_001002010, NM_001002009, BC071652, BC066914, BC015856,

Species

human

UniGene ID

Hs.487933

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.