human NRG2 Over-expression AAV

Name 
AAV-h-NRG2
Cat No 
AAV-217076
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human NRG2.

AAV-217076
AAV-h-NRG2

Ready-to-use AAV expressing Human NRG2 (neuregulin 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DON1; HRG2; NTAK
Description (Vector)
NRG2 encodes a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ERBB family of receptors, this protein induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1, another member of the neuregulin family of ligands. The products of these genes mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. NRG2 is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease. Alternative transcript variants encoding distinct isoforms have been described.
Gene ID
9542
Gene Name (Vector)
neuregulin 2
Gene Symbol
NRG2
HGNC ID
HGNC:7998
ORF Size (aa)
2559
ORF Size (bp)
2559 bp
RefSeq ID
NM_004883
RefSeq Synonyms
NM_013983, NM_013982, NM_013981, NM_004883, NM_001184935, BC166615,
Species
human
UniGene ID
Hs.408515

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.