human NFKBIA Over-expression AAV

Name 
AAV-h-NFKBIA
Cat No 
AAV-216647
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human NFKBIA.

AAV-216647
AAV-h-NFKBIA

Ready-to-use AAV expressing Human NFKBIA (NFKB inhibitor alpha). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
IKBA; MAD-3; NFKBI
Description (Vector)
NFKBIA encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.
Gene ID
4792
Gene Name (Vector)
NFKB inhibitor alpha
Gene Symbol
NFKBIA
HGNC ID
HGNC:7797
ORF Size (aa)
954
ORF Size (bp)
954 bp
RefSeq ID
NM_020529
RefSeq Synonyms
NM_020529, BC004983, BC002601,
Species
human
UniGene ID
Hs.81328

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.