human NDUFS1 Over-expression AAV

Name 
AAV-h-NDUFS1
Cat No 
AAV-216520
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human NDUFS1.

AAV-216520
AAV-h-NDUFS1

Ready-to-use AAV expressing Human NDUFS1 (NADH:ubiquinone oxidoreductase core subunit S1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CI-75k; CI-75Kd; PRO1304
Description (Vector)
NDUFS1 belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene.
Gene ID
4719
Gene Name (Vector)
NADH:ubiquinone oxidoreductase core subunit S1
Gene Symbol
NDUFS1
HGNC ID
HGNC:7707
ORF Size (aa)
2184
ORF Size (bp)
2184 bp
RefSeq ID
NM_005006
RefSeq Synonyms
NM_005006, NM_001199984, NM_001199983, NM_001199982, NM_001199981, BC030833, BC022368, BC012068,
Species
human
UniGene ID
Hs.471207

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.