human NCR3 Over-expression AAV

Name
AAV-h-NCR3

Cat No
AAV-216433

Availability
4-5 weeks

This is an AAV expressing Human NCR3.

AAV-216433

AAV-h-NCR3

Ready-to-use AAV expressing Human NCR3 (natural cytotoxicity triggering receptor 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

1C7; CD337; LY117; MALS; NKp30

Description (Vector)

NCR3 is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.

Gene ID

259197

Gene Name (Vector)

natural cytotoxicity triggering receptor 3

Gene Symbol

NCR3

HGNC ID

HGNC:19077

ORF Size (aa)

534

RefSeq ID

NM_147130

RefSeq Synonyms

NM_147130, NM_001145467, NM_001145466, BC052582, BC018752,

Species

human

UniGene ID

Hs.509513

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.