human NACC2 Over-expression AAV

Name 
AAV-h-NACC2
Cat No 
AAV-216281
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human NACC2.

AAV-216281
AAV-h-NACC2

Ready-to-use AAV expressing Human NACC2 (NACC family member 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BEN domain containing 9; BEND9; BTB (POZ) domain containing 14A; BTB/POZ domain-containing protein 14A; BTBD14; BTBD14A; BTBD31; NAC-2; NACC family member 2, BEN and BTB (POZ) domain containing; nucleus accumbens-associated protein 2; RBB; repressor with BTB domain and BEN domain; transcription repressor with a BTB domain and a BEN domain
Description (eCommerce)
NACC2/BTBD14A functions as a transcriptional repressor through its association with the NuRD complex. NACC2/BTBD14A recruits the NuRD complex to the promoter of MDM2, leading to the repression of MDM2 transcription and subsequent stability of p53/TP53 [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96BF6].
Gene ID
138151
Gene Name (eCommerce)
NACC family member 2
Gene Name (Vector)
NACC family member 2
Gene Symbol
NACC2
HGNC ID
HGNC:23846
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1764
ORF Size (bp)
1764 bp
Protein Name (eCommerce)
Nucleus accumbens-associated protein 2
RefSeq ID
NM_144653
RefSeq Synonyms
NM_144653, BC015649,
Research Areas
Cell Biology,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
NACC2/BTBD14A functions as a transcriptional repressor through its association with the NuRD complex. NACC2/BTBD14A recruits the NuRD complex to the promoter of MDM2, leading to the repression of MDM2 transcription and subsequent stability of p53/TP53 [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96BF6].
UniGene ID
Hs.112895
UniProt ID (eCommerce)
Q96BF6

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.