human MYOZ2 Over-expression AAV

Name 
AAV-h-MYOZ2
Cat No 
AAV-216236
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human MYOZ2.

AAV-216236
AAV-h-MYOZ2

Ready-to-use AAV expressing Human MYOZ2 (myozenin 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C4orf5; CMH16; CS-1
Description (Vector)
MYOZ2 belongs to a family of sarcomeric proteins that bind to calcineurin, a phosphatase involved in calcium-dependent signal transduction in diverse cell types. These family members tether calcineurin to alpha-actinin at the z-line of the sarcomere of cardiac and skeletal muscle cells, and thus they are important for calcineurin signaling. Mutations in this gene cause cardiomyopathy familial hypertrophic type 16, a hereditary heart disorder.
Gene ID
51778
Gene Name (Vector)
myozenin 2
Gene Symbol
MYOZ2
HGNC ID
HGNC:1330
ORF Size (aa)
795
RefSeq ID
NM_016599
RefSeq Synonyms
NM_016599, BC020932, BC017402, BC005195,
Species
human
UniGene ID
Hs.381047

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.