human MYOZ2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human MYOZ2.
shAAV-216236
AAV-h-MYOZ2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human MYOZ2 (myozenin 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C4orf5; CMH16; CS-1
Description (Vector)
MYOZ2 belongs to a family of sarcomeric proteins that bind to calcineurin, a phosphatase involved in calcium-dependent signal transduction in diverse cell types. These family members tether calcineurin to alpha-actinin at the z-line of the sarcomere of cardiac and skeletal muscle cells, and thus they are important for calcineurin signaling. Mutations in this gene cause cardiomyopathy familial hypertrophic type 16, a hereditary heart disorder.
Gene ID
51778
Gene Name (Vector)
myozenin 2
Gene Symbol
MYOZ2
HGNC ID
HGNC:1330
ORF Size (aa)
795
RefSeq ID
NM_016599
RefSeq Synonyms
NM_016599, BC020932, BC017402, BC005195,
Species
human
UniGene ID
Hs.381047
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.