human MGLL Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-215424
Availability:
3-5 weeks
Name:
AAV-h-MGLL
This is an AAV expressing Human MGLL.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- MGLL
- Gene Name
- monoglyceride lipase
- Gene ID
- 11343
- Gene Synonyms
- HU-K5; HUK5; MAGL; MGL
- ORF Size
- 942 bp
- RefSeq#
- BC006230
- Gene Description
- MGLL encodes a serine hydrolase of the AB hydrolase superfamily that catalyzes the conversion of monoacylglycerides to free fatty acids and glycerol. The encoded protein plays a critical role in several physiological processes including pain and nociperception through hydrolysis of the endocannabinoid 2-arachidonoylglycerol. Expression of this gene may play a role in cancer tumorigenesis and metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
- UniGene ID
- Hs.277035
- HGNC ID
- HGNC:17038
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