human CCBP2 Over-expression AAV
This is an AAV expressing Human ACKR2.
AAV-214392
AAV-h-CCBP2
Ready-to-use AAV expressing Human ACKR2 (atypical chemokine receptor 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CCBP2; CCR10; CCR9; CMKBR9; D6; hD6
Description (Vector)
CCBP2 encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. CCBP2 is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. CCBP2 is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes.
Gene ID
1238
Gene Name (Vector)
atypical chemokine receptor 2
Gene Symbol
ACKR2
HGNC ID
HGNC:1565
ORF Size (aa)
1155
ORF Size (bp)
1155 bp
RefSeq ID
NM_001296
RefSeq Synonyms
NM_001296, BC112045, BC101629, BC020558, BC011631, BC008816,
Species
human
UniGene ID
Hs.146346
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.