human PSCA Over-expression AAV

Name 
AAV-h-PSCA
Cat No 
AAV-214165
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PSCA.

AAV-214165
AAV-h-PSCA

Ready-to-use AAV expressing Human PSCA (prostate stem cell antigen). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
PRO232
Description (Vector)
PSCA encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. PSCA is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. PSCA includes a polymorphism that results in an upstream start codon in some individuals; this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants.
Gene ID
8000
Gene Name (Vector)
prostate stem cell antigen
Gene Symbol
PSCA
HGNC ID
HGNC:9500
ORF Size (aa)
372
RefSeq ID
NM_005672
RefSeq Synonyms
NM_005672, BC065183, BC023582,
Species
human
UniGene ID
Hs.711174

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.