human PTDSS2 Over-expression AAV

Name
AAV-h-PTDSS2

Cat No
AAV-214136

Availability
4-5 weeks

This is an AAV expressing Human PTDSS2.

AAV-214136

AAV-h-PTDSS2

Ready-to-use AAV expressing Human PTDSS2 (phosphatidylserine synthase 2). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

PSS2

Description (Vector)

Phosphatidylserine (PS) accounts for 5 to 10% of cell membrane phospholipids. In addition to its role as a structural component, PS is involved in cell signaling, blood coagulation, and apoptosis. PS is synthesized by a calcium-dependent base-exchange reaction catalyzed by PS synthases (EC 2.7.8.8), like PTDSS2, that exchange L-serine for the polar head group of phosphatidylcholine (PC) or phosphatidylethanolamine (PE) (Sturbois-Balcerzak et al., 2001 (PubMed 11084049)).(supplied by OMIM, May 2009)

Gene ID

81490

Gene Name (Vector)

phosphatidylserine synthase 2

Gene Symbol

PTDSS2

HGNC ID

HGNC:15463

ORF Size (aa)

1464

ORF Size (bp)

1464 bp

RefSeq ID

NM_030783

RefSeq Synonyms

NM_030783, NM_001329548, NM_001329545, NM_001329544, BC001210,

Species

human

UniGene ID

Hs.12851

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.