human SNAP25 Over-expression AAV

Name 
AAV-h-SNAP25
Cat No 
AAV-214114
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SNAP25.

AAV-214114
AAV-h-SNAP25

Ready-to-use AAV expressing Human SNAP25 (synaptosome associated protein 25). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
bA416N4.2; CMS18; dJ1068F16.2; RIC-4; RIC4; SEC9; SNAP; SNAP-25; SUP
Description (Vector)
Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene.
Gene ID
6616
Gene Name (Vector)
synaptosome associated protein 25
Gene Symbol
SNAP25
HGNC ID
HGNC:11132
ORF Size (aa)
621
RefSeq ID
NM_003081
RefSeq Synonyms
NM_130811, NM_003081, NM_001322910, NM_001322909, NM_001322908, NM_001322907, NM_001322906, NM_001322905, NM_001322904, NM_001322903, NM_001322902, BC010647,
Species
human
UniGene ID
Hs.167317

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.