human LILRB3 Over-expression AAV
This is an AAV expressing Human LILRB3.
AAV-213935
AAV-h-LILRB3
Ready-to-use AAV expressing Human LILRB3 (leukocyte immunoglobulin like receptor B3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CD85A; HL9; ILT-5; ILT5; LILRA6; LIR-3; LIR3; PIR-B; PIRB
Description (Vector)
LILRB3 is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
11025
Gene Name (Vector)
leukocyte immunoglobulin like receptor B3
Gene Symbol
LILRB3
HGNC ID
HGNC:6607
ORF Size (aa)
1896
ORF Size (bp)
1896 bp
RefSeq ID
NM_006864
RefSeq Synonyms
NM_006864, NM_001320960, NM_001081450, BC112198, BC104993,
Species
human
UniGene ID
Hs.688335
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.