human LAX1 Over-expression AAV

Name 
AAV-h-LAX1
Cat No 
AAV-213709
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human LAX1.

AAV-213709
AAV-h-LAX1

Ready-to-use AAV expressing Human LAX1 (lymphocyte transmembrane adaptor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
LAT-like membrane associated protein; LAX; linker for activation of x cells; lymphocyte transmembrane adapter 1; membrane-associated adapter protein LAX
Description (eCommerce)
LAX1 negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8IWV1].
Gene ID
54900
Gene Name (eCommerce)
lymphocyte transmembrane adaptor 1
Gene Name (Vector)
lymphocyte transmembrane adaptor 1
Gene Symbol
LAX1
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1197
ORF Size (bp)
1197 bp
Protein Name (eCommerce)
Lymphocyte transmembrane adapter 1
RefSeq ID
NM_017773
RefSeq Synonyms
NM_017773, NM_001282878, NM_001136190, BC089408, BC069650,
Research Areas
Golgi Apparatus,Immunology,Signal Transduction,T-cell Receptor Signaling
Research Areas (Faceted)
signal_transduction,cell_biology,immunology,signal_transduction
Species
human
Target Sentence
LAX1 negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8IWV1].
UniGene ID
Hs.272794
UniProt ID (eCommerce)
Q8IWV1

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.