human LAX1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human LAX1.
shADV-213709
Ad-h-LAX1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human LAX1 (lymphocyte transmembrane adaptor 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
LAT-like membrane associated protein; LAX; linker for activation of x cells; lymphocyte transmembrane adapter 1; membrane-associated adapter protein LAX
Description (eCommerce)
LAX1 negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8IWV1].
Gene ID
54900
Gene Name (eCommerce)
lymphocyte transmembrane adaptor 1
Gene Name (Vector)
lymphocyte transmembrane adaptor 1
Gene Symbol
LAX1
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1197
ORF Size (bp)
1197 bp
Protein Name (eCommerce)
Lymphocyte transmembrane adapter 1
RefSeq ID
NM_017773
RefSeq Synonyms
NM_017773, NM_001282878, NM_001136190, BC089408, BC069650,
Research Areas
Golgi Apparatus,Immunology,Signal Transduction,T-cell Receptor Signaling
Research Areas (Faceted)
signal_transduction,cell_biology,immunology,signal_transduction
Species
human
Target Sentence
LAX1 negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8IWV1].
UniGene ID
Hs.272794
UniProt ID (eCommerce)
Q8IWV1
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.