human KLHDC5 Over-expression AAV

Name 
AAV-h-KLHDC5
Cat No 
AAV-213216
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human KLHL42.

AAV-213216
AAV-h-KLHDC5

Ready-to-use AAV expressing Human KLHL42 (kelch like family member 42). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Ctb9; cullin-3-binding protein 9; kelch domain containing 5; kelch domain-containing protein 5; kelch-like protein 42; KLHDC5
Description (eCommerce)
Kelch-like protein 42 (KLHL42) is a substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL42) E3 ubiquitin ligase complex mediates the ubiquitination and subsequent degradation of KATNA1. Involved in microtubule dynamics throughout mitosis [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9P2K6].
Gene ID
57542
Gene Name (eCommerce)
kelch like family member 42
Gene Name (Vector)
kelch like family member 42
Gene Symbol
KLHL42
HGNC ID
HGNC:29252
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1518
ORF Size (bp)
1518 bp
Protein Name (eCommerce)
Kelch-like protein 42
RefSeq ID
NM_020782
RefSeq Synonyms
NM_020782, BC137117, BC137116, BC108669,
Research Areas
Cell Cycle,Cell Division,Cytoskeleton
Research Areas (Faceted)
cell_biology,cell_cycle,genetics
Species
human
Target Sentence
Kelch-like protein 42 (KLHL42) is a substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL42) E3 ubiquitin ligase complex mediates the ubiquitination and subsequent degradation of KATNA1. Involved in microtubule dynamics throughout mitosis [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9P2K6].
UniGene ID
Hs.505104
UniProt ID (eCommerce)
Q9P2K6

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.