human KLF5 Over-expression AAV

Name 
AAV-h-KLF5
Cat No 
AAV-213192
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human KLF5.

AAV-213192
AAV-h-KLF5

Ready-to-use AAV expressing Human KLF5 (Kruppel like factor 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
basic transcription element binding protein 2; Basic transcription element-binding protein 2; BTEB2; BTE-binding protein 2; CKLF; colon krueppel-like factor; colon kruppel-like factor; epididymis secretory sperm binding protein; GC box binding protein 2; GC-box-binding protein 2; IKLF; intestinal Kruppel-like factor; intestinal-enriched krueppel-like factor; intestinal-enriched kruppel-like factor; Klf5C isoform; Krueppel-like factor 5; Kruppel-like factor 5 (intestinal); transcription factor BTEB2
Description (eCommerce)
KLF5 a member of the Kruppel-like factor subfamily of zinc finger proteins. KLF5 is a transcriptional activator that acts downstream of multiple different signaling pathways and is regulated by post-translational modification. It may participate in both promoting and suppressing cell proliferation. Expression of this gene may be changed in a variety of different cancers and in cardiovascular disease. [taken from NCBI Entrez Gene (Gene ID: 688)].
Description (Vector)
KLF5 encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. Since the protein localizes to the nucleus and binds the epidermal growth factor response element, it is thought to be a transcription factor.
Gene ID
688
Gene Name (eCommerce)
Kruppel like factor 5
Gene Name (Vector)
Kruppel like factor 5
Gene Symbol
KLF5
HGNC ID
HGNC:6349
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1374
ORF Size (bp)
1374 bp
Protein Name (eCommerce)
Krueppel-like factor 5
RefSeq ID
NM_001730
RefSeq Synonyms
NM_001730, NM_001286818, BC042131, BC007695,
Research Areas
Angiogenesis,Golgi Apparatus,Transcription Factor/Regulator,Zinc-finger
Research Areas (Faceted)
cancer,cell_biology,developmental_biology,transcription_translation
Species
human
Target Sentence
KLF5 a member of the Kruppel-like factor subfamily of zinc finger proteins. KLF5 is a transcriptional activator that acts downstream of multiple different signaling pathways and is regulated by post-translational modification. It may participate in both promoting and suppressing cell proliferation. Expression of this gene may be changed in a variety of different cancers and in cardiovascular disease. [taken from NCBI Entrez Gene (Gene ID: 688)].
UniGene ID
Hs.508234
UniProt ID (eCommerce)
Q13887

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.