human KLF1 Over-expression AAV

Name 
AAV-h-KLF1
Cat No 
AAV-213172
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human KLF1.

AAV-213172
AAV-h-KLF1

Ready-to-use AAV expressing Human KLF1 (Kruppel like factor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
EKLF
Description (Vector)
KLF1 encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype.
Gene ID
10661
Gene Name (Vector)
Kruppel like factor 1
Gene Symbol
KLF1
HGNC ID
HGNC:6345
ORF Size (aa)
1089
ORF Size (bp)
1089 bp
RefSeq ID
NM_006563
RefSeq Synonyms
NM_006563, BC033580,
Species
human
UniGene ID
Hs.37860

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.