human KIRREL3 Over-expression AAV

Name 
AAV-h-KIRREL3
Cat No 
AAV-213149
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human KIRREL3.

AAV-213149
AAV-h-KIRREL3

Ready-to-use AAV expressing Human KIRREL3 (kin of IRRE like 3 (Drosophila)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
KIRRE; MRD4; NEPH2; PRO4502
Description (Vector)
KIRREL3 is a member of the nephrin-like protein family. These proteins are expressed in fetal and adult brain, and also in podocytes of kidney glomeruli. The cytoplasmic domains of these proteins interact with the C-terminus of podocin, also expressed in the podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. Mutations in this gene are associated with mental retardation autosomal dominant type 4 (MRD4). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
84623
Gene Name (Vector)
kin of IRRE like 3 (Drosophila)
Gene Symbol
KIRREL3
HGNC ID
HGNC:23204
ORF Size (aa)
2337
ORF Size (bp)
2337 bp
RefSeq ID
NM_032531
RefSeq Synonyms
NM_032531, NM_001301097, NM_001161707, BC101801, BC101775,
Species
human
UniGene ID
Hs.657065

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.