human SIK3 Over-expression AAV

Name 
AAV-h-SIK3
Cat No 
AAV-212963
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SIK3.

AAV-212963
AAV-h-SIK3

Ready-to-use AAV expressing Human SIK3 (SIK family kinase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
L19; QSK; salt-inducible kinase 3; serine/threonine-protein kinase QSK; serine/threonine-protein kinase SIK3; SIK-3
Description (eCommerce)
Salt-inducible kinase 3 (SIK3), also known as QSK, is a member of a subfamily of serine/threonine protein kinases related to AMP-activated protein kinase (AMPK). The family consists of SIK1, SIK2, and SIK3. Although SIK3 is ubiquitously expressed, the SIK kinases are suggested to regulate signal transduction specifically in adrenal and adipose tissues.
Gene ID
23387
Gene Name (eCommerce)
SIK family kinase 3
Gene Name (Vector)
SIK family kinase 3
Gene Symbol
SIK3
HGNC ID
HGNC:29165
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3309
ORF Size (bp)
3309 bp
Protein Name (eCommerce)
Serine/threonine-protein kinase SIK3
RefSeq ID
NM_025164
RefSeq Synonyms
NM_025164, NM_001281749, NM_001281748, BC128511, BC128510,
Research Areas
Kinase/Phosphatase,LKB1 Signaling,Signal Transduction
Research Areas (Faceted)
signal_transduction,cell_biology
Species
human
Target Sentence
Salt-inducible kinase 3 (SIK3), also known as QSK, is a member of a subfamily of serine/threonine protein kinases related to AMP-activated protein kinase (AMPK). The family consists of SIK1, SIK2, and SIK3. Although SIK3 is ubiquitously expressed, the SIK kinases are suggested to regulate signal transduction specifically in adrenal and adipose tissues.
UniGene ID
Hs.167451
UniProt ID (eCommerce)
Q9Y2K2

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.