human SIK3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SIK3.
shAAV-212963
AAV-h-SIK3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SIK3 (SIK family kinase 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
L19; QSK; salt-inducible kinase 3; serine/threonine-protein kinase QSK; serine/threonine-protein kinase SIK3; SIK-3
Description (eCommerce)
Salt-inducible kinase 3 (SIK3), also known as QSK, is a member of a subfamily of serine/threonine protein kinases related to AMP-activated protein kinase (AMPK). The family consists of SIK1, SIK2, and SIK3. Although SIK3 is ubiquitously expressed, the SIK kinases are suggested to regulate signal transduction specifically in adrenal and adipose tissues.
Gene ID
23387
Gene Name (eCommerce)
SIK family kinase 3
Gene Name (Vector)
SIK family kinase 3
Gene Symbol
SIK3
HGNC ID
HGNC:29165
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3309
ORF Size (bp)
3309 bp
Protein Name (eCommerce)
Serine/threonine-protein kinase SIK3
RefSeq ID
NM_025164
RefSeq Synonyms
NM_025164, NM_001281749, NM_001281748, BC128511, BC128510,
Research Areas
Kinase/Phosphatase,LKB1 Signaling,Signal Transduction
Research Areas (Faceted)
signal_transduction,cell_biology
Species
human
Target Sentence
Salt-inducible kinase 3 (SIK3), also known as QSK, is a member of a subfamily of serine/threonine protein kinases related to AMP-activated protein kinase (AMPK). The family consists of SIK1, SIK2, and SIK3. Although SIK3 is ubiquitously expressed, the SIK kinases are suggested to regulate signal transduction specifically in adrenal and adipose tissues.
UniGene ID
Hs.167451
UniProt ID (eCommerce)
Q9Y2K2
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.