human KDM4B Over-expression AAV

Name
AAV-h-KDM4B

Cat No
AAV-212843

Availability
4-5 weeks

This is an AAV expressing Human KDM4B.

AAV-212843

AAV-h-KDM4B

Ready-to-use AAV expressing Human KDM4B (lysine demethylase 4B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

jmjC domain-containing histone demethylation protein 3B; JMJD2B; jumonji domain containing 2B; jumonji domain-containing protein 2B; lysine (K)-specific demethylase 4B; lysine-specific demethylase 4B; TDRD14B; tudor domain containing 14B

Description (eCommerce)

JMJD2B is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in chromatin regulation and influences transcriptional activation and suppression. JMJD2B has been shown to be capable of antagonizing H3K9 trimethylation.

Gene ID

23030

Gene Name (eCommerce)

lysine demethylase 4B

Gene Name (Vector)

lysine demethylase 4B

Gene Symbol

KDM4B

HGNC ID

HGNC:29136

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

3291

ORF Size (bp)

3291 bp

Protein Name (eCommerce)

Lysine-specific demethylase 4B

RefSeq ID

NM_015015

RefSeq Synonyms

NM_015015, BC144292, BC136611, BC063889,

Research Areas

Cancer,Chromatin Remodeling,Transcription Factor/Regulator,Zinc-finger

Research Areas (Faceted)

cancer,cell_biology,genetics,transcription_translation

Species

human

Target Sentence

UniGene ID

Hs.654816

UniProt ID (eCommerce)

O94953

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.