mouse KDM4B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Kdm4b.
shAAV-262764
AAV-m-KDM4B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Kdm4b (lysine (K)-specific demethylase 4B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
4732474L06Rik; Jmjd2b; mKIAA0876
Description (Vector)
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.
Gene ID
193796
Gene Name (Vector)
lysine (K)-specific demethylase 4B
Gene Symbol
Kdm4b
ORF Size (aa)
3261
ORF Size (bp)
3261 bp
RefSeq ID
NM_172132
RefSeq Synonyms
NM_172132, BC007145,
Species
mouse
UniGene ID
Mm.45047
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.