human KAT2B Over-expression AAV

Name 
AAV-h-KAT2B
Cat No 
AAV-212627
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human KAT2B.

AAV-212627
AAV-h-KAT2B

Ready-to-use AAV expressing Human KAT2B (lysine acetyltransferase 2B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CAF; CREBBP-associated factor; histone acetylase PCAF; histone acetyltransferase KAT2B; histone acetyltransferase PCAF; K(lysine) acetyltransferase 2B; Lysine acetyltransferase 2B; P/CAF; p300/CBP-associated factor; PCAF
Description (eCommerce)
PCAF (P300/CBP-associated factor) is a histone acetyltransferase (HAT) identified as a factor that associates with P300/CBP, a transcriptional coactivator of nuclear hormone receptors and other transcription factors.
Description (Vector)
CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.
Gene ID
8850
Gene Name (eCommerce)
lysine acetyltransferase 2B
Gene Name (Vector)
lysine acetyltransferase 2B
Gene Symbol
KAT2B
HGNC ID
HGNC:8638
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2499
ORF Size (bp)
2499 bp
Protein Name (eCommerce)
Histone acetyltransferase KAT2B
RefSeq ID
NM_003884
RefSeq Synonyms
NM_003884, BC070075, BC060823,
Research Areas
Acyltransferase,Cancer,Cell Cycle,Chromatin Remodeling,FoxO Signaling,Gene Expression,Histone Modification,Host-Virus Interactions,Notch Signaling,p53 Signaling,Signal Transduction,TGF-beta Signaling,Transcription Factor/Regulator,Viral Carcinogenesis
Research Areas (Faceted)
cancer,signal_transduction,cell_biology,cell_cycle,transcription_translation,signal_transduction,genetics,transcription_translation,infectious_disease,developmental_biology,signal_transduction,immunology,genetics,transcription_translation,cancer,infectious_disease
Species
human
Target Sentence
PCAF (P300/CBP-associated factor) is a histone acetyltransferase (HAT) identified as a factor that associates with P300/CBP, a transcriptional coactivator of nuclear hormone receptors and other transcription factors.
UniGene ID
Hs.533055
UniProt ID (eCommerce)
Q92831

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.