human JDP2 Over-expression AAV

Name 
AAV-h-JDP2
Cat No 
AAV-212580
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human JDP2.

AAV-212580
AAV-h-JDP2

Ready-to-use AAV expressing Human JDP2 (Jun dimerization protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
jun dimerization protein 2; JUNDM2; progesterone receptor co-activator
Description (eCommerce)
JDP2 is a component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. JDP2 is involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. It can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8WYK2].
Gene ID
122953
Gene Name (eCommerce)
Jun dimerization protein 2
Gene Name (Vector)
Jun dimerization protein 2
Gene Symbol
JDP2
HGNC ID
HGNC:17546
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
492
ORF Size (bp)
492 bp
Protein Name (eCommerce)
Jun dimerization protein 2
RefSeq ID
NM_130469
RefSeq Synonyms
NM_130469, NM_001135049, NM_001135048, NM_001135047, BC051303,
Research Areas
Histone Modification,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
JDP2 is a component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. JDP2 is involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. It can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8WYK2].
UniGene ID
Hs.196482
UniProt ID (eCommerce)
Q8WYK2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.