human ITPKA Over-expression AAV

Name
AAV-h-ITPKA

Cat No
AAV-212546

Availability
4-5 weeks

This is an AAV expressing Human ITPKA.

AAV-212546

AAV-h-ITPKA

Ready-to-use AAV expressing Human ITPKA (inositol-trisphosphate 3-kinase A). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

IP3-3KA; IP3KA

Description (Vector)

Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.

Gene ID

3706

Gene Name (Vector)

inositol-trisphosphate 3-kinase A

Gene Symbol

ITPKA

HGNC ID

HGNC:6178

ORF Size (aa)

1386

ORF Size (bp)

1386 bp

RefSeq ID

NM_002220

RefSeq Synonyms

NM_002220, BC026331,

Species

human

UniGene ID

Hs.2722

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.