human ISL1 Over-expression AAV

Name 
AAV-h-ISL1
Cat No 
AAV-212438
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ISL1.

AAV-212438
AAV-h-ISL1

Ready-to-use AAV expressing Human ISL1 (ISL LIM homeobox 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Isl-1; ISLET1
Description (Vector)
ISL1 encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.
Gene ID
3670
Gene Name (Vector)
ISL LIM homeobox 1
Gene Symbol
ISL1
HGNC ID
HGNC:6132
ORF Size (aa)
1050
ORF Size (bp)
1050 bp
RefSeq ID
NM_002202
RefSeq Synonyms
NM_002202, BC031213,
Species
human
UniGene ID
Hs.505

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.