human IRF8 Over-expression AAV

Name 
AAV-h-IRF8
Cat No 
AAV-212413
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human IRF8.

AAV-212413
AAV-h-IRF8

Ready-to-use AAV expressing Human IRF8 (interferon regulatory factor 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
H-ICSBP; ICSBP; ICSBP1; IMD32A; IMD32B; IRF-8
Description (Vector)
Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.
Gene ID
3394
Gene Name (Vector)
interferon regulatory factor 8
Gene Symbol
IRF8
HGNC ID
HGNC:5358
ORF Size (aa)
1281
ORF Size (bp)
1281 bp
RefSeq ID
NM_002163
RefSeq Synonyms
NM_002163, BC126247,
Species
human
UniGene ID
Hs.137427

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.