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human IRF2BP2 Over-expression AAV

Name 
AAV-h-IRF2BP2
Cat No 
AAV-212404
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human IRF2BP2.

AAV-212404
AAV-h-IRF2BP2

Ready-to-use AAV expressing Human IRF2BP2 (interferon regulatory factor 2 binding protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CVID14; interferon regulatory factor 2-binding protein 2; IRF-2-binding protein 2; IRF-2BP2
Description (eCommerce)
Interferon regulatory factor-2-binding protein-2 (IRF2BP1) is a transcriptional co-repressor of IRF2 (interferon regulatory factor-2). IRF2BP2 has also been shown to play a role in cell survival during stress responses involving p53. IRF2BP2 is also a component of the TEAD4/BGLL4 transcription factor complex involved in the regulation of VEGFA expression.
Description (Vector)
IRF2BP2 encodes an interferon regulatory factor-2 (IRF2) binding protein that interacts with the C-terminal transcriptional repression domain of IRF2. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Gene ID
359948
Gene Name (eCommerce)
interferon regulatory factor 2 binding protein 2
Gene Name (Vector)
interferon regulatory factor 2 binding protein 2
Gene Symbol
IRF2BP2
HGNC ID
HGNC:21729
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1764
ORF Size (bp)
1764 bp
Protein Name (eCommerce)
Interferon regulatory factor 2-binding protein 2
RefSeq ID
NM_182972
RefSeq Synonyms
NM_182972, NM_001077397, BC160054,
Research Areas
Transcription Factor/Regulator,Zinc-finger
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
Interferon regulatory factor-2-binding protein-2 (IRF2BP1) is a transcriptional co-repressor of IRF2 (interferon regulatory factor-2). IRF2BP2 has also been shown to play a role in cell survival during stress responses involving p53. IRF2BP2 is also a component of the TEAD4/BGLL4 transcription factor complex involved in the regulation of VEGFA expression.
UniGene ID
Hs.693837
UniProt ID (eCommerce)
Q7Z5L9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.