human IRF2BP1 Over-expression AAV

Name
AAV-h-IRF2BP1

Cat No
AAV-212401

Availability
4-5 weeks

This is an AAV expressing Human IRF2BP1.

AAV-212401

AAV-h-IRF2BP1

Ready-to-use AAV expressing Human IRF2BP1 (interferon regulatory factor 2 binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

interferon regulatory factor 2-binding protein 1; IRF-2-binding protein 1; IRF-2BP1; probable E3 ubiquitin-protein ligase IRF2BP1; probable RING-type E3 ubiquitin transferase IRF2BP1

Description (eCommerce)

Interferon regulatory factor-2-binding protein-2 (IRF2BP1) is a transcriptional co-repressor of IRF2 (interferon regulatory factor-2). IRF2BP2 has also been shown to play a role in cell survival during stress responses involving p53. IRF2BP2 is also a component of the TEAD4/BGLL4 transcription factor complex involved in the regulation of VEGFA expression.

Gene ID

26145

Gene Name (eCommerce)

interferon regulatory factor 2 binding protein 1

Gene Name (Vector)

interferon regulatory factor 2 binding protein 1

Gene Symbol

IRF2BP1

HGNC ID

HGNC:21728

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1755

ORF Size (bp)

1755 bp

Protein Name (eCommerce)

Interferon regulatory factor 2-binding protein 1

RefSeq ID

NM_015649

RefSeq Synonyms

NM_015649, BC078181, BC039002, BC038222,

Research Areas

Signal Transduction,TGF-beta Signaling,Transcription Factor/Regulator,Zinc-finger

Research Areas (Faceted)

cell_biology,immunology,signal_transduction,transcription_translation

Species

human

Target Sentence

Interferon regulatory factor-2-binding protein-2 (IRF2BP1) is a transcriptional co-repressor of IRF2 (interferon regulatory factor-2). IRF2BP2 has also been shown to play a role in cell survival during stress responses involving p53. IRF2BP2 is also a component of the TEAD4/BGLL4 transcription factor complex involved in the regulation of VEGFA expression.

UniGene ID

Hs.515477

UniProt ID (eCommerce)

Q8IU81

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.