human IRAK3 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-212394
Availability:
3-5 weeks
Name:
AAV-h-IRAK3
This is an AAV expressing Human IRAK3.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- IRAK3
- Gene Name
- interleukin 1 receptor associated kinase 3
- Gene ID
- 11213
- Gene Synonyms
- ASRT5; IRAKM
- ORF Size
- 1791 bp
- RefSeq#
- BC069388
- Gene Description
- IRAK3 encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants.
- UniGene ID
- Hs.369265
- HGNC ID
- HGNC:17020
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