human IRAK1 Over-expression AAV

Name 
AAV-h-IRAK1
Cat No 
AAV-212390
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human IRAK1.

AAV-212390
AAV-h-IRAK1

Ready-to-use AAV expressing Human IRAK1 (interleukin 1 receptor associated kinase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
interleukin-1 receptor-associated kinase 1; IRAK; IRAK-1; pelle; Pelle homolog
Description (eCommerce)
Interleukin-1 receptor-associated kinase 1 (IRAK1) is one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK1 is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B [taken from NCBI Entrez Gene (Gene ID: 3654)].
Description (Vector)
IRAK1 encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK1 is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
3654
Gene Name (eCommerce)
interleukin 1 receptor associated kinase 1
Gene Name (Vector)
interleukin 1 receptor associated kinase 1
Gene Symbol
IRAK1
HGNC ID
HGNC:6112
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1902
ORF Size (bp)
1902 bp
Protein Name (eCommerce)
Interleukin-1 receptor-associated kinase 1
RefSeq ID
NM_001569
RefSeq Synonyms
NM_001569, NM_001025243, NM_001025242, BC054000, BC014963,
Research Areas
Apoptosis,Cytokine Signaling,EPO Signaling,Host-Virus Interactions,Immunology,Innate Immunity,Interleukin Signaling,JAK-STAT Signaling,Kinase/Phosphatase,MAPK Signaling,Neurobiology,NF-kB Signaling,NGF Signaling,Signal Transduction,Toll-like Receptor Signaling,Transcription Factor/Regulator,VEGF Signaling
Research Areas (Faceted)
cell_biology,immunology,infectious_disease,neurobiology,signal_transduction,transcription_translation
Species
human
Target Sentence
Interleukin-1 receptor-associated kinase 1 (IRAK1) is one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK1 is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B [taken from NCBI Entrez Gene (Gene ID: 3654)].
UniGene ID
Hs.522819
UniProt ID (eCommerce)
P51617

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.