human INTS4 Over-expression AAV

Name 
AAV-h-INTS4
Cat No 
AAV-212321
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human INTS4.

AAV-212321
AAV-h-INTS4

Ready-to-use AAV expressing Human INTS4 (integrator complex subunit 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
INT4; integrator complex subunit 4; MST093; MSTP093
Description (eCommerce)
INT4 has been identified as a component of the twelve-subunit integrator complex that functions in RNA Pol II mediated 3’-end mRNA processing of the U1 and U2 small nuclear RNAs (snRNAs).
Description (Vector)
INTS4 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 (PubMed 16239144)).(supplied by OMIM, Mar 2008)
Gene ID
92105
Gene Name (eCommerce)
integrator complex subunit 4
Gene Name (Vector)
integrator complex subunit 4
Gene Symbol
INTS4
HGNC ID
HGNC:25048
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1533
ORF Size (bp)
1533 bp
Protein Name (eCommerce)
Integrator complex subunit 4
RefSeq ID
NM_033547
RefSeq Synonyms
NM_033547, BC015664, BC009995,
Research Areas
RNA Processing
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
INT4 has been identified as a component of the twelve-subunit integrator complex that functions in RNA Pol II mediated 3’-end mRNA processing of the U1 and U2 small nuclear RNAs (snRNAs).
UniGene ID
Hs.533723
UniProt ID (eCommerce)
Q96HW7

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AAV-h-INTS4

Cat No: AAV-212322

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.