human INSIG1 Over-expression AAV

Name 
AAV-h-INSIG1
Cat No 
AAV-212302
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human INSIG1.

AAV-212302
AAV-h-INSIG1

Ready-to-use AAV expressing Human INSIG1 (insulin induced gene 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CL6
Description (Vector)
Oxysterols regulate cholesterol homeostasis through the liver X receptor (LXR)- and sterol regulatory element-binding protein (SREBP)-mediated signaling pathways. This gene is an insulin-induced gene. It encodes an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. This protein binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Gene ID
3638
Gene Name (Vector)
insulin induced gene 1
Gene Symbol
INSIG1
HGNC ID
HGNC:6083
ORF Size (aa)
834
RefSeq ID
NM_005542
RefSeq Synonyms
NM_198337, NM_198336, NM_005542, NM_001346594, NM_001346593, NM_001346592, NM_001346591, NM_001346590, BC001880,
Species
human
UniGene ID
Hs.520819

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.