human IL1RAP Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-212110
Availability:
3-5 weeks
Name:
AAV-h-IL1RAP
This is an AAV expressing Human IL1RAP.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- IL1RAP
- Gene Name
- interleukin 1 receptor accessory protein
- Gene ID
- 3556
- Gene Synonyms
- C3orf13; IL-1RAcP; IL1R3
- ORF Size
- 1071 bp
- RefSeq#
- BC053621
- Gene Description
- Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms, one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress.
- UniGene ID
- Hs.478673
- HGNC ID
- HGNC:5995
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