human IL1A Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-212089
Availability:
3-5 weeks
Name:
AAV-h-IL1A
This is an AAV expressing Human IL1A.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- IL1A
- Gene Name
- interleukin 1 alpha
- Gene ID
- 3552
- Gene Synonyms
- IL-1A; IL1; IL1-ALPHA; IL1F1
- ORF Size
- 816 bp
- RefSeq#
- BC013142
- Gene Description
- IL1A is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.
- UniGene ID
- Hs.1722
- HGNC ID
- HGNC:5991
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