human IL18R1 Over-expression AAV

Name 
AAV-h-IL18R1
Cat No 
AAV-212080
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human IL18R1.

AAV-212080
AAV-h-IL18R1

Ready-to-use AAV expressing Human IL18R1 (interleukin 18 receptor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CD antigen CD218a; CD218 antigen-like family member A; CD218a; CDw218a; cytokine receptor; IL1 receptor-related protein; IL-18R1; IL-18R-1; IL18RA; IL-18Ralpha; IL-18R-alpha; IL18Ralpha2; IL1RRP; IL-1Rrp; IL1R-rp; interleukin-18 receptor 1; interleukin-18 receptor alpha
Description (eCommerce)
IL18R1 a cytokine receptor that belongs to the interleukin 1 receptor family. It specifically binds interleukin 18 (IL18) and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of IL18R1 in NK and T cells. [taken from NCBI Entrez Gene (Gene ID: 8809)].
Description (Vector)
IL18R1 is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q.
Gene ID
8809
Gene Name (eCommerce)
interleukin 18 receptor 1
Gene Name (Vector)
interleukin 18 receptor 1
Gene Symbol
IL18R1
HGNC ID
HGNC:5988
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1623
ORF Size (bp)
1623 bp
Protein Name (eCommerce)
Interleukin-18 receptor 1
RefSeq ID
NM_003855
RefSeq Synonyms
NM_003855, NM_001282399, BC143403, BC093977, BC093975, BC069575,
Research Areas
Immunology,Innate Immunity,Interleukin Signaling,JAK-STAT Signaling,Signal Transduction,TNF Signaling
Research Areas (Faceted)
signal_transduction,immunology
Species
human
Target Sentence
IL18R1 a cytokine receptor that belongs to the interleukin 1 receptor family. It specifically binds interleukin 18 (IL18) and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of IL18R1 in NK and T cells. [taken from NCBI Entrez Gene (Gene ID: 8809)].
UniGene ID
Hs.469521
UniProt ID (eCommerce)
Q13478

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.