human IKZF3 Over-expression AAV

Name 
AAV-h-IKZF3
Cat No 
AAV-212019
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human IKZF3.

AAV-212019
AAV-h-IKZF3

Ready-to-use AAV expressing Human IKZF3 (IKAROS family zinc finger 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AIO; AIOLOS; ZNFN1A3
Description (Vector)
IKZF3 encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. IKZF3 product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants.
Gene ID
22806
Gene Name (Vector)
IKAROS family zinc finger 3
Gene Symbol
IKZF3
HGNC ID
HGNC:13178
ORF Size (aa)
1530
ORF Size (bp)
1530 bp
RefSeq ID
NM_012481
RefSeq Synonyms
NM_183232, NM_183231, NM_183230, NM_183229, NM_183228, NM_012481, NM_001284516, NM_001284515, NM_001284514, NM_001257414, NM_001257413, NM_001257412, NM_001257411, NM_001257410, NM_001257409, NM_001257408, BC032707,
Species
human
UniGene ID
Hs.444388

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.