human IKBKG Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-212012
Availability:
3-5 weeks
Name:
AAV-h-IKBKG
This is an AAV expressing Human IKBKG.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- IKBKG
- Gene Name
- inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
- Gene ID
- 8517
- Gene Synonyms
- AMCBX1; FIP-3; FIP3; Fip3p; IKK-gamma; IKKAP1; IKKG; IMD33; IP; IP1; IP2; IPD2; NEMO; ZC2HC9
- ORF Size
- 1260 bp
- RefSeq#
- BC046922
- Gene Description
- IKBKG encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.
- UniGene ID
- Hs.43505
- HGNC ID
- HGNC:5961
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