human IGF2 Over-expression AAV

Name 
AAV-h-IGF2
Cat No 
AAV-211914
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human IGF2.

AAV-211914
AAV-h-IGF2

Ready-to-use AAV expressing Human IGF2 (insulin like growth factor 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C11orf43; GRDF; IGF-II; PP9974
Description (Vector)
IGF2 encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
3481
Gene Name (Vector)
insulin like growth factor 2
Gene Symbol
IGF2
HGNC ID
HGNC:5466
ORF Size (aa)
543
RefSeq ID
NM_001007139
RefSeq Synonyms
NM_001291862, NM_001291861, NM_001127598, NM_001007139, NM_000612, BC042127, BC000531,
Species
human
UniGene ID
Hs.718427

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.