human IFITM5 Over-expression AAV

Name 
AAV-h-IFITM5
Cat No 
AAV-211818
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human IFITM5.

AAV-211818
AAV-h-IFITM5

Ready-to-use AAV expressing Human IFITM5 (interferon induced transmembrane protein 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BRIL; DSPA1; fragilis4; Hrmp1; OI5
Description (Vector)
IFITM5 encodes a membrane protein thought to play a role in bone mineralization. IFITM5 is located on chromosome 11 in a cluster of related genes which are induced by interferon, however, this gene has not been shown to be interferon inducible. A similar gene, located in a gene cluster on mouse chromosome 7, is a member of the interferon-inducible fragilis gene family. The mouse gene encodes a transmembrane protein described as participating in germ cell competence. A mutation in the 5' UTR of this gene has been associated with osteogenesis imperfecta type V (PMID: 22863190, 22863195).
Gene ID
387733
Gene Name (Vector)
interferon induced transmembrane protein 5
Gene Symbol
IFITM5
HGNC ID
HGNC:16644
ORF Size (aa)
396
RefSeq ID
NM_001025295
RefSeq Synonyms
NM_001025295, BC156992, BC156100, BC150563, BC150562,
Species
human
UniGene ID
Hs.443469

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.