human ICMT Over-expression AAV

Name
AAV-h-ICMT

Cat No
AAV-211756

Availability
4-5 weeks

This is an AAV expressing Human ICMT.

AAV-211756

AAV-h-ICMT

Ready-to-use AAV expressing Human ICMT (isoprenylcysteine carboxyl methyltransferase). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HSTE14; MST098; MSTP098; PCCMT; PCMT; PPMT

Description (Vector)

ICMT encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined.

Gene ID

23463

Gene Name (Vector)

isoprenylcysteine carboxyl methyltransferase

Gene Symbol

ICMT

HGNC ID

HGNC:5350

ORF Size (aa)

855

ORF Size (bp)

855 bp

RefSeq ID

NM_012405

RefSeq Synonyms

NM_012405, BC028168,

Species

human

UniGene ID

Hs.515688

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.